Ethylene glycol toxicosis is a type of poisoning that occurs after ingestion of antifreeze or other fluids containing the ingredient ethylene glycol. Ethylene glycol is metabolized in the animal’s body to several extremely toxic chemicals that are responsible for its potentially lethal effects. Without treatment, ethylene glycol toxicity is most often fatal.

Ethylene glycol affects the nervous system and causes severe kidney failure with almost complete cessation of urine output. Definitive treatment should be started as soon as possible after consumption of ethylene glycol (within a few hours). If treated promptly and appropriately, pets that have consumed ethylene glycol will not develop kidney failure and have a good chance of survival.

Diagnosis and Treatment Notes:

  • Ethylene glycol toxicity is generally diagnosed with a thorough history and physical examination, bloodwork, urinalysis and an ethylene gycol test. In some cases, a kidney biopsy may be necessary.
  • Treatment depends on the severity of the disease, your individual pet, and your veterinarian. Pets with ethylene glycol toxicity are generally treated with drugs that may induce vomiting if the ingestion was recent, activated charcoal, fluids, and medication aimed at reducing the toxicity of the ethylene glycol. The drugs most commonly used to reduce the effects of ethylene glycol are  ethanol or 4-methylpyrazole. Dogs with acute kidney failure require more extensive therapy including dialysis.  Discuss treatment details when your pet is diagnosed with this condition.


What to Watch for*:

  • Vomiting
  • Drooling
  • Increased thirst and increased urination
  • Lethargy
  • Stumbling and staggering (acting drunk)
  • Coma

Please notify us if you notice any of the above signs or if you have any questions!

Dear Valued Clients

During these challenging times, there have been some unforeseen changes at The Big Easy Animal Hospital. I cannot express enough my sincere apology for any inconvenience you have experienced at The Big Easy during these times. As we strive to make the practice safe to protect everyone including you, your family, and our Big Easy team and their families, I’ve decided to make certain changes while we are under this pandemic. These changes will be temporary.


Monday, Tuesday, Thursday & Friday:
Walk Ins: Check-in starts at 9:45am.There are a limited amount of patients we can accept. Our receptionists will be happy to assist you with options to help guide you and your pet(s).)


Saturday Hours

Saturdays will be TECHNICIAN APPOINTMENTS only. These will include boosters, bloodwork, nail trims, certain diagnostics, etc. There will not be a veterinarian on site. While I understand these changes can be inconvenient, I have listed local veterinary clinics that we have contacted and are open to see walk-ins throughout the week and Saturdays as well. For life threatening emergencies that occur outside business hours, please contact the following 24-hour animal hospitals below.

Please, be safe and healthy.

Thank you all for your understanding. -Aileen Ruiz, DVM


24 Hour Emergency Care:


Pittsburgh Veterinary Specialty and Emergency Center

807 Camp Horne Road
Pittsburgh, PA



4224 Northern Pike
Monroeville, PA

VCA Castle Shannon Animal Hospital

3610 Library Road
Pittsburgh, PA

Veterinarians Accepting Walk in Care:

Penn Animal Hospital

2205 Penn Avenue

North Boros Veterinary Hospital

2255 Babcock Blvd



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